Project details
Nuclear Envelope Project: The nuclear envelope is a double membrane that surrounds our genomic DNA. Mutations in genes that make nuclear envelope proteins cause a collection of diseases called laminopathies. This project involves analysis of mutant nuclear envelope proteins and how they cause rare types of muscular dystrophy and heart disease. Fruit fly models and human muscle biopsy tissues are being used for investigation.
mRNA Splicing Factor Project: Mutations in the gene SNRNP200 cause a rare vision disorder called Retinitis Pigmentosa (RP). Research is focused on understanding how mutations in a mRNA splicing factor that is needed in all cells in the body causes eye-specific disease. Research is being carried out on fruit fly and mouse models (RP).
Qualifications Courses in biology, biochemistry, and fundamental genetics preferred.
Time Commitment
12-15 hours/week
Compensation
Volunteer
Academic Credit
Start Date
Near future
Immediate
Timeline
Ongoing, potential to be a continuous position
How to apply
E-mail lori-wallrath@uiowa.ed with cover letter, current resume and hours available.