Current Undergraduate Opportunities

Lipotoxicity in metabolic diseases

Our research seeks to understand how lipotoxic lipid metabolites ceramides impair nutrient sensing and leads to the development of metabolic diseases. The students will have the opportunity to acquire multiple skills in bioinformatics, molecular, biochemical, and cellular assays as well as mouse handling (if comfortable) and be co-authors on scientific manuscripts.

Skin, epidermal development and cleft lip and palate

The research performed in the Dunnwald lab aims at elucidating mechanisms of epithelial cell adhesion and migration in the context of epidermal development (skin) and craniofacial development (cleft lip and palate). The lab uses a variety of models, including mice and cell culture, and a wide variety of techniques, including microscopy, biochemistry, histology and immunofluorescence.

Epigenetics in cancer progression and control

Our lab is interesting in learning how changes in DNA accessibility (epigenetics) contribute to gene expression changes that drive cancer progression and resistance to therapy. The trainee will work closely with a research scientist and the principal investigator to learn and apply new techniques. There are opportunities for both wet-lab and bioinformatic research.

How early epigenetic programming of the human genome in T cells enable them to have long-lasting fitness and function in health and disease

The project would be to establish a new assay in the laboratory. The trainee will work closely with a research scientist and PI in the lab and be involved in day-to-day lab operations.

Immune pathogenesis of graft-versus-host disease and inflammatory bowel diseases

We are interested in working with motivated undergraduate students who can spend time in the laboratory to learn intestinal immunology and advance their laboratory skills. Intestinal immune system is associated with regulation of aberrant immune reactions, as seen in graft-versus-host disease after bone marrow or hematopoietic cell transplantation or in inflammatory bowel diseases. Our studies focus on T lymphocytes and gut microorganisms, such as helminths or gut bacteria that can regulate these aberrant and pathological immune responses. Students will purify immune cells from spleen or lymph nodes, characterize them in detail by multicolor flow cytometry, perform in vitro immune cell cultures besides various other experiments. Students will analyze DNA for various reasons.

How health lifestyle behaviors effect cognitive and brain aging

The goal of our research is to determine how health and health behaviors effect cognitive and brain aging. This includes examining mechanisms associated with declines in cognitive function associated with aging or age-related neurological disease, and determining how we may intervene for improved performance and quality of life. To study health behaviors, we are interested in how people learn new behaviors or improve cognitive abilities to do so, and the lifestyle factors that effect cognition, behavior change, and brain wellness.

Understanding Genome Size and Ploidy Level Variation Through Elemental Analyses

The Neiman lab is using ecological stoichiometry to study the evolution of genome architecture in a freshwater New Zealand snail, Potamopyrgus antipodarum, that features unique natural genomic variation. We are addressing whether this variation could be linked to differential sensitivity to nutrient limitation, with the prediction that snails with larger genomes will need more of the elements used to build genomes to be healthy.

Obesity, Diabetes, and CVD

Our research aims to identify the molecular components of integration between organelle stress responses that are in play in obesity and diabetes at the cellular and organismic levels.

Uterine Endometrial Cancer: Molecular Mechanisms, Targeted Therapy

Uterine endometrial cancer incidence (~65,950 new cases/year) and deaths (~12,550 deaths/year) are on the rise. To help endometrial cancer patients and cure endometrial cancer, we need understand the characteristics of this disease. The current focus of our work is to understand molecular mechanisms of endometrial tumor progression and utilize target therapy or molecular enhanced hormonal therapy to treat endometrial cancer and other hormone-driven cancers.

Learning-Based High-Dimensional Magnetic Resonance Imaging

Students are expected to code/run deep learning algorithms to solve specific problems in biomedical imaging.

Cognitive Control and Action Selection

The research assistants will be invited to participate in all aspects of psychological research relating to the organization of voluntary action. We are primarily interested in how individuals select their responses as they perform one or more tasks. Research assistants will run human participants in 45-minute experiments and engage in any other aspects of the research that interests them, including experimental design, programming the experiments and data analysis.
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Neurobiology of alcohol dependence and neurodegeneration

Alcohol and Neurodegeneration Lab, Neuroscience and Pharmacology

Our group is focused on understanding the molecular and circuit adaptations following alcohol abuse and chronic stress that predispose to psychiatric disorders, neurodegenerative disease and infectious disease. 

Gut Microbiome Interbacterial Interactions

Bosch Lab, Department of Pathology

We study how bacteria interact in the gut microbiome in healthy people, and in the context of gastrointestinal diseases. We apply a broad range of techniques including metagenomic sequencing, proteomics, bacteriology, genetics, and structural biology. 

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Mechanisms by ion channels and transporters mediate transport of ions across cellular membranes

Chowdhury Lab

We are interested in understanding how ions and small molecules are transported across the oily cellular membranes. We specialize in membrane protein biochemistry and biophysics, determining atomic resolution snapshots of protein complexes.

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Neurocognitive basis of parent-child interactions and child development

Development, Experience and Neurocognition Lab

Research assistants will have the opportunity to assist with various lab procedures (e.g., collecting data during child lab visits, data management, and video coding of parent–child interactions). 

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Molecular basis and gene therapy of cystic fibrosis

Engelhardt Research Lab, Anatomy and Cell Biology

We are looking for undergraduate students who are interested in research and learning techniques that will help with general lab duties including aliquoting, cell work, chemical making, cleanup, and lab upkeep. No experience is needed; we are willing to train you!

Neural and cognitive mechanisms of executive function

Hwang Lab, Neurocognitive Dynamics

The Hwang lab conducts research to understand the neural mechanisms of executive functions. Research assistants will gain valuable experience with cognitive neuroscience research, assisting with subject recruitment, behavioral/EEG/TMS/fMRI data collection, quality control of neuroimaging data, and execution of data analyses.

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Gastroenterology research about muscle layer and mucosa

Kurahashi Lab, Division of Gastroenterology and Hepatology

We invite passionate undergraduates to delve into groundbreaking gastroenterology research in advancing our understanding of the gastrointestinal (GI) tract, specifically focusing on its muscle layer and mucosa.

Genetic regulation of endoderm development

Lin Lab, Anatomy and Cell Biology

The goal of our laboratory's research is to understand the genetic regulation of endoderm development, which is a germ layer critical for craniofacial structures and the digestive system. We use zebrafish as the animal model.  

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Sleep disturbance in psychiatric disorders

Neurodevelopment and Psychopathology Lab

We focus on defining the physiological features of sleep disturbances in psychiatric disorders, investigating their relations with symptoms and cognitive deficits, and examining the neural circuitry involved in these sleep deficits using neuroimaging and electrophysiology techniques.

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Physiology of ion transporting epithelia

Thornell Lab, Internal Medicine

Our projects are captured by the question “How do the different kinds of cells work together in an epithelium to orchestrate ion transport?”. Duties include making solutions, help in preparing experiments, and mouse genotyping. 

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Experimental fluid dynamics, naval hydrodynamics, flow diagnosis

Wang Lab

For undergraduate students who are interested in experimental fluid dynamics, there are several on-going research projects including sustainable drag reduction and developing an in-house laser illumination system.

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Cellular and Molecular mechanisms of Obesity/Diabetes

Yang Lab, Anatomy and Cell Biology

Our research aims to identify the molecular components of integration between organelle stress responses that are in play in obesity and diabetes at the cellular and organismic levels. 

Learning-Based High-Dimensional Magnetic Resonance Imaging

Multiparametric Quantitative MRI Group

Students are expected to code/run deep learning algorithms to solve specific problems in biomedical imaging. Qualifications STEM background. 
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Understanding novel genes in cardiac and neurological systems and disease

Boudreau Lab, Internal Medicine

The Boudreau Lab is working to discover new genes that regulate healthy heart and brain functions. We are looking for energetic students who are interested in learning advanced techniques to help us with general lab duties.

Social-Emotional Development from Infancy to Adolescence

Child Lab, Psychological Brain Sciences

We study children’s social-emotional development from infancy to adolescence. Students in this lab have the opportunity to work on a longitudinal study to help collect data during laboratory sessions, code behavioral data from videos, and perform preliminary data management. We prefer students with experience working with young children.

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Central nervous system control of metabolic homeostasis and sleep-wake behavior

Cui Lab, Neuroscience and Pharmacology

Research projects in our lab aim to uncover the complex brain networks and signaling mechanisms that control metabolic homeostasis and sleep-wake behavior using mouse as a model organism. 

Development of behavior problems and positive adjustment in children

Developmental Psychopathology Lab

We conduct research to understand how children develop behavior problems as well as positive adjustment. To study the development of behavior problems we examine brain development, sleep, stress, parenting, temperament, and language skills.

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Neural Mechanisms Underlying Motivated Behaviors

The Flippo Lab

We are looking for undergraduates interested in neuroscience research investigating how the brain influences reward seeking and fear behaviors. Duties will include performing experiments in rodents and day-to-day tasks in the lab. 

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Human Brain Research and Technologies

Iowa NeuroBank Core, Iowa Neuroscience Institute

This position offers hands-on experience and research skills by working with a human brain bank and associated technologies, as well as outreach events. We are seeking a current senior with a major in neuroscience, biology, or human physiology. 

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Analysis of environmental contaminants in biological samples

Lehmler Lab, Occupational and Environmental Health

We are looking for student research assistants who would like to investigate the role of persistent organic pollutants in adverse health effects. The research project involves the analysis of environmental contaminants in biological samples.

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Impact of insulin signaling and FoxOs on muscle mitochondria and strength

Molecular Biology Lab

We are looking for an undergraduate researcher in a Molecular Biology lab who is willing to learn basic lab protocols (PCR, western blot, enzymatic assays) and be willing to handle mouse models. This position has the potential to grow into an independent project.

Brain Mechanisms of Learning and Memory

Neuroscience of Learning and Memory Lab

We conduct research on the brain mechanisms underlying learning and memory in humans, rats, and mice. Our experiments involve cutting-edge neuroscience techniques to study how information is learned and stored in the brain.

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Human rights in Culture, Religion, Politics, and Law

Souaiaia Lab, Religious Studies

The research project (Media Narratives on Armed Conflicts) is interdisciplinary requiring the use of many tools and skills, including large data analysis, digital content creation, preliminary research answering specific research questions, and integration of digital content in classroom teaching. 

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Dietary and lifestyle approaches to improving quality of life in Multiple Sclerosis

Wahls Lab, Internal Medicine

The Wahls Research lab is interested in the relationship between diet quality and clinical outcomes. The study Efficacy of Diet on Quality of Life in Multiple Sclerosis is a five year study, completing in 2027.  

Cognitive Neuroscience

Wessel Cognitive Neuroscience Lab

At the Wessel Cognitive Neuroscience Lab, undergraduate research assistants will run Cognitive Neuroscience tasks with EEG and TMS neuroimaging techniques. No lab experience required. A minimum GPA of 3.5 is required.

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