Current Undergraduate Opportunities
Neural Circuits and Behavior Core Research
This lab focuses on performing mouse behavioral experiments for studying brain function in health and disease. This position offers the opportunity to learn and apply cutting edge systems and circuit-level neuroscience tools to study the neural basis of behavior in a mouse model.
Arlene Holden Laboratory for Breast Cancer Research
Understanding how breast cancer undergoes metastasis and becomes resistant to treatment.
Robert Louis Katz and Manne Research Institute Summer Scholars Program
This program offers undergraduate students the chance to gain a paid, hands-on research experience focused on childhood health and disease
Molecular Regulation of Vascular Function
Our group is focused on understanding the cellular signaling pathways involved in vascular disease. We conduct both cell biology and animal studies to investigate the role of novel proteins or processes in endothelial cell biology. Students with an interest in cell biology or animal studies are encouraged to apply.
Duties and responsibilities: performing cell based studies, genotyping, managing mice colonies, microscopy all these will depend on the experience and interest.
Radiation Biology and Physics Undergraduate Research Summer Program
Research opportunities available in radiation therapy, redox biology, cancer biology, traditional and medical physics, engineering, medical imaging, immunology and more.
Unveiling GPCR signaling in cancer and obesity: function and therapeutic options
The research focuses on investigating the signaling mechanisms underlying the development of obesity and breast cancer. This project offers ample opportunities for undergraduate student involvement. Depending on their experience, students may assist with lab maintenance, support experimental procedures, and receive guidance in applying for the ICRU fellowship. With substantial contributions, students may also have the opportunity to co-author manuscripts.
Conventional and Stereotypes in Award-Winning Photojournalism
The Visual Media Lab in the School of Journalism and Mass Communication is looking for an undergraduate research assistant for a project involving web scraping and data organization. This position is ideal for students interested in applying their programming skills to real-world research in a collaborative and open science environment.
Learning-Based High-Dimensional Magnetic Resonance Imaging
Students are expected to code/run deep learning algorithms to solve specific problems in biomedical imaging.
Sleep Disturbance in Psychiatric Disorders
Students in this lab will have the opportunity to assist data collection in behavioral, sleep EEG or MRI experiments, organize and maintain databases, and aid in preprocessing of data. They may receive training on EEG and MRI data acquisition, sleep scoring, RedCap, and MRI safety. This is an attractive position for those who are interested in pursuing graduate careers in neuroscience, clinical or cognitive psychology in the future. There is opportunity to conduct honor theses if the student’s research interest aligns with the goals of our lab, and they demonstrate commitment and excellence.
Cellular and Molecular Mechanisms of Obesity/Diabetes
Our research aims to identify the molecular components of integration between organelle stress responses that are in play in obesity and diabetes at the cellular organismic levels.
Human Rights in Context
In this position students can learn new perspectives and consider the ways human rights might apply to their vocational interests, developing a critical proficiency in human rights in an increasingly complex and interconnected world. Our work on human rights is done through a holistic approach, incorporating insight from a plurality of disciplines. Students will be able to choose from several options, all of which will enable them to learn and conduct research on human rights.
Evolution of Stress Response Networks in Yeast Pathogens
We are looking for motivated students with a strong interest in research as a career, and eager to gain skills in molecular biology, fungal genetics and bioinformatic data analysis. Research projects in the lab span a wide range of topics but are mostly focused on understanding the evolution of stress response regulation in a group of yeast species. This group includes several opportunistic pathogens that based on our preliminary data have rewired their stress response networks.
Neural Mechanisms Underlying Motivated Behaviors
We are looking for undergraduates interested in neuroscience research investigating how the brain influences reward seeking and fear behaviors.
Genetic Regulation of Endoderm Development
We are currently seeking undergraduate students to join our research team. The students will be responsible for zebrafish care and fish genotyping and will also receive relevant training to conduct experiments. Students will have opportunities to be involved in specific projects and contribute to publications.
Human Brain and Research Technologies
This position offers hands-on experience and research skills by working with a human brain bank and associated technologies. You will assist with administrative tasks, research biospecimen collection, microscopic imaging, preparation of reagents and material, analysis of human specimens, and assisting the outreach events and workshops.
Development of Behavior Problems and Positive Adjustment in Children
The Developmental Psychopathology Lab conducts research to understand how children develop behavior problems as well as positive adjustment. We have been particularly interested in externalizing behavior problems, such as aggressive, disruptive, and noncompliant behavior. We focus on the development of self-regulation skills and the consequences of children’s self-regulation skills (or deficits) for their school readiness. The goal of our lab is to improve understanding about how children develop behavior problems from a very early age (3–7 years).
Dietary and Lifestyle Approaches to Improving Quality of Life in Multiple Sclerosis
The Wahls Research lab is interested in the relationship between diet quality and clinical outcomes. Motor function is assessed using timed walk and hand function tests. Vision function, quality of life and blood biomarkers are also assessed. The study Efficacy of Diet on Quality of Life in Multiple Sclerosis is a five year study, completing in 2027.
Gastroenterology research about muscle layer and mucosa
Our team is committed to advancing our understanding of the gastrointestinal (GI) tract, specifically focusing on its muscle layer and mucosa. Our ultimate aim is to translate our foundational scientific discoveries into clinical studies, paving the way for innovative treatments for GI diseases.
Neurobiology of Alcohol Dependence and Neurodegeneration
Our group is focused on understanding the molecular and circuit adaptations following alcohol abuse and chronic stress that predispose to psychiatric disorders, neurodegenerative disease and infectious disease.
Social-Emotional Development from Infancy to Adolescence
We study children’s social-emotional development from infancy to adolescence. Students in this lab have the opportunity to work on a longitudinal study to help collect data during laboratory sessions, code behavioral data from videos, and perform preliminary data management.
Central Nervous System Control of Metabolic Homeostasis and Sleep-Wake Behavior
Research projects in our lab aim to uncover the complex brain networks and signaling mechanisms that control metabolic homeostasis and sleep-wake behavior using mouse as a model organism. Students will first learn the state-of-the-art neuroscience techniques, including optogenetics, chemogenetics and in vivo fiber photometry, and then help different research projects led by postdocs and research scientists.
Mechanisms by ion channels and transporters mediate transport of ions across cellular membranes
The Chowdhury Lab is interested in understanding how ions and small molecules are transported across the oily cellular membranes. Such processes are not only critical for cellular survival, they underlie the electrical activity of neurons, cardiac myocytes etc. The lab specializes in membrane protein biochemistry and biophysics and uses multi-disciplinary approaches to determine atomic resolution snapshots of protein complexes, mediating these transport processes, at different stages of their function.
Neural and cognitive mechanisms of executive function
The Hwang lab conducts research to understand the neural mechanisms of executive functions. Specifically, we are interested in discovering the neural architecture, processes, and dynamic systems that allow brain networks to select, inhibit, transfer, and integrate information. Together, these mechanisms support many important mental functions, such as attention, working memory, response selection and inhibition. We address our research questions with a comprehensive human neuroscience approach, combining multimodal research methodologies, including fMRI, EEG, TMS, eye tracking and behavioral testing.
Research assistants will gain valuable experience with cognitive neuroscience research. Specifically, the research assistant will assist with subject recruitment, behavioral/EEG/TMS/fMRI data collection, quality control of neuroimaging data, and execution of data analyses. If motivated, the applicant will also have the opportunity to learn advanced neuroimaging methods and develop research projects. Assistants are also encouraged to attend regular journal clubs to discuss the most up-to-date scientific literature.
Understanding Novel Genes in Cardiac and Neurological Systems and Disease
The Boudreau Lab is working to discover new genes that regulate healthy heart functions. We are looking for energetic students who are interested in learning advanced techniques to help us with general lab duties.
Neurocognitive Basis of Parent-Child Interactions and Child Development
Research assistants will have the opportunity to assist with various lab procedures (e.g., collecting data during child lab visits, data management, and video coding of parent–child interactions). Students will also have the opportunity to gain experience in data collection and analysis in fNIRS and MRI experiments.
Brain Mechanisms of Learning and Memory
We conduct research on the brain mechanisms underlying learning and memory in humans, rats, and mice. Our experiments involve cutting-edge neuroscience techniques to study how information is learned and stored in the brain.
Neuroendocrine Tumors and Other Rare Cancer Models.
We are developing novel rare cancer models for drug testing and understanding tumor biology. We are recruiting students who would like to do research for the Undergrad Honor's Research course and seeking publication opportunity.
Pancreas Cancer and Microbiome Drug Metabolism
The focus of our lab is on pancreas cancer and microbiome drug metabolism.
We are looking for an undergrad research assistant to help with the following tasks:
1) Culture cancer cells and perform drug testing
2) Prepare common solutions
3) Sterilization of research equipment
4) Manage biohazard waste
5) Stock up lab inventory
Gut Microbiome Interbacterial Interactions
Our laboratory studies interbacterial interactions among colonic commensals. Altered composition of the gut microbiome contributes to many disease states, and targeted manipulation holds therapeutic promise. The intestinal microbiome is a complex ecosystem where bacteria occupy overlapping niches. Bacteria contact one another, eliciting responses which may neutral, competitive, or collaborative. Bacteroidetes comprise one of the dominant phyla in the human gut microbiome and are known to compete with diverse species to colonize and persist in the intestine. As part of their fitness for the colonic environment, Bacteroidetes utilize a remarkable diversity of carbon sources, and some encode type VI secretion systems which deliver effectors (toxins) to kill contacting bacteria. Genomes of these Bacteroidetes also encode immunity proteins which prevent intoxication of self and kin.
Immunology research on neuroinflammation and intestinal inflammation
My laboratory has two major research interests: Neuroimmunology and Mucosal Immunology. In Neuroimmunology, we study the regional immunity/inflammation in central nervous system, either in animal model of Multiple Sclerosis (MS) which is an autoimmune demyelinating disease, or in animal model of Parkinson’s disease which is a neurodegenerative disease. The aim is to understand the role of neuroinflammation in the pathogenesis of the two diseases. In Mucosal Immunology, we focus on the role of LRRK2-mediated innate immunity, such as inflammasome activation, in host defense and intestinal inflammation.
Cancer genetics and bioinformatics to identify genetic drivers of cancer progression and treatment resistance.
The Dupuy is currently recruiting an undergraduate research assistant to support ongoing projects in the lab. Research in the Dupuy lab is focused on cancer genetics and bioinformatics to identify genetic drivers of cancer progression and treatment resistance.
Studying the Maintenance of Sex and other Big Questions, Mostly in Snails
The Neiman lab uses a variety of conceptual approaches, tools, and methods to study various questions involving the evolution of sexual reproduction, often by studying a small New Zealand snail species that is a powerful model system for the study of sex. We also use the snails to address other topics, including the consequences of plastic pollution, effects of temperature change on learning and memory, and how nutrient availability might influence genome evolution. We also engage in science outreach activities around the Iowa City community.
We don’t have a specific opening for specific project available right now, but curious, positive, and team-oriented students interested in any of these topics should reach out to Dr. Neiman to discuss potential opportunities. There are always ways for motivated and inquisitive undergraduates to contribute!
Immune regulation of graft-versus-host disease and inflammatory bowel disease
We are looking for enthusiastic and motivated undergraduate students who are interested in immunology and want to investigate intestinal mucosa in two disease models, namely graft-versus-host disease and inflammatory bowel disease.
Lipotoxicity in metabolic diseases
Our research seeks to understand how lipotoxic lipid metabolites ceramides impair nutrient sensing and leads to the development of metabolic diseases. The students will have the opportunity to acquire multiple skills in bioinformatics, molecular, biochemical, and cellular assays as well as mouse handling (if comfortable) and be co-authors on scientific manuscripts.
Epigenetics in cancer progression and control
Our lab is interesting in learning how changes in DNA accessibility (epigenetics) contribute to gene expression changes that drive cancer progression and resistance to therapy.
The trainee will work closely with a research scientist and the principal investigator to learn and apply new techniques. There are opportunities for both wet-lab and bioinformatic research.
How early epigenetic programming of the human genome in T cells enable them to have long-lasting fitness and function in health and disease
The project would be to establish a new assay in the laboratory. The trainee will work closely with a research scientist and PI in the lab and be involved in day-to-day lab operations.
Immune pathogenesis of graft-versus-host disease and inflammatory bowel diseases
We are interested in working with motivated undergraduate students who can spend time in the laboratory to learn intestinal immunology and advance their laboratory skills. Intestinal immune system is associated with regulation of aberrant immune reactions, as seen in graft-versus-host disease after bone marrow or hematopoietic cell transplantation or in inflammatory bowel diseases. Our studies focus on T lymphocytes and gut microorganisms, such as helminths or gut bacteria that can regulate these aberrant and pathological immune responses. Students will purify immune cells from spleen or lymph nodes, characterize them in detail by multicolor flow cytometry, perform in vitro immune cell cultures besides various other experiments. Students will analyze DNA for various reasons.
Obesity, Diabetes, and CVD
Our research aims to identify the molecular components of integration between organelle stress responses that are in play in obesity and diabetes at the cellular and organismic levels.
Uterine Endometrial Cancer: Molecular Mechanisms, Targeted Therapy
Uterine endometrial cancer incidence (~65,950 new cases/year) and deaths (~12,550 deaths/year) are on the rise. To help endometrial cancer patients and cure endometrial cancer, we need understand the characteristics of this disease. The current focus of our work is to understand molecular mechanisms of endometrial tumor progression and utilize target therapy or molecular enhanced hormonal therapy to treat endometrial cancer and other hormone-driven cancers.
Experimental fluid dynamics, Naval hydrodynamics, Flow diagnosis
For undergraduate students who are interested in experimental fluid dynamics, there are several on-going research projects including sustainable drag reduction and developing an in-house laser illumination system.
Physiology of Ion Transporting Epithelia
Our projects are captured by the question “How do the different kinds of cells work together in an epithelium to orchestrate ion transport?”. Duties include making solutions, help in preparing experiments, and mouse genotyping.
Cognitive Control and Action Selection
The research assistants will be invited to participate in all aspects of psychological research relating to the organization of voluntary action. We are primarily interested in how individuals select their responses as they perform one or more tasks. Research assistants will run human participants in 45-minute experiments and engage in any other aspects of the research that interests them, including experimental design, programming the experiments and data analysis.