Project and Position Details
In the Gene Regulatory Evolution (GRE) lab, we study how stress response networks evolve between related yeast species that live in different environments. Compared with the model yeast S. cerevisiae, which humans have domesticated for brewing and baking, the related C. glabrata is an opportunistic pathogen and is the second most frequent cause of Candidemia in patients. Taking advantage of this pair of genetically related yet ecologically diverged species, we aim to dissect the key differences in how they regulate their orthologous stress response networks by focusing on functional divergence in the transcription factor proteins and their target genes in these networks. In terms of approach, we integrate molecular genetics, bioinformatics, evolutionary genetics and biochemistry tools, and thus offer a multitude of training opportunities. We strongly value intellectual development and team-building, and undergraduate researchers have always been a key part of our team. We also strongly encourage underrepresented minority students, first-generation students and students from rural and low economic-social backgrounds to join us!

To learn more about our research, follow our website at binhe-lab.org

Qualifications
A strong interest in biology, especially genetics and evolution; strong commitment and highly responsible; willing to work hard and not be afraid of making mistakes and repeated failures.

Time Commitment
Depends on the student's schedule, but generally 5-10 hr / wk during the semester and 10-15 hr/wk during the summer is needed to make meaningful progress.

Start Date
Immediate
Near future
Summer semester
Fall semester
Spring semester
TBD

Project Duration 
Ongoing, potential to be a continuous position

Compensation
Academic Credit
Volunteer
Pay

Apply by
May 31, 2022

How to Apply
Email bin-he@uiowa.edu with a brief description of your year of study, academic interest, goal in undergrad research, career plan, and please attach a resume.